Publications by authors named "S Mavin"
Article Synopsis
- Lyme Borreliosis (LB), or Lyme disease, is increasingly concerning due to its severe health risks from untreated cases, often diagnosed too late with current tests having low sensitivity.
- A new diagnostic test, the Epitogen Lyme Detect IgG ELISA, was validated in this study using 220 serum samples to assess sensitivity and specificity against the standard LIAISON Borrelia IgG test.
- The Epitogen test showed comparable performance for late stages of LB and significantly higher sensitivity for early suspected cases, indicating it could improve early and accurate diagnosis of Lyme disease.
Article Synopsis
- * Using national Scottish data, the study finds that individuals with five or more conditions are significantly more likely to test negative for antibodies post-vaccination and have a much higher risk of COVID-19 hospitalization or death.
- * There's a clear link showing that lower antibody levels after vaccination are associated with increased risks of severe outcomes, including hospitalization and death, indicating the importance of monitoring antibody levels in vaccinated individuals.
Background: The true burden of Lyme disease in primary care in Scotland is unknown. Epidemiological data are currently based on laboratory-confirmed reports as there is no mandatory reporting of clinical cases.
Aim: To analyse data from general practice in NHS Highland (North) over a 6-year period to assess the incidence and management of Lyme disease in primary care.
As part of the NorthTick project, co-funded by the European Union through the European Regional Development Fund and the North Sea Region Programme, specialists in the field of tick-borne diseases from seven North Sea countries co-operated with patient organisations and governmental health care institutions to provide this comprehensive overview of diagnostics and treatment recommendations in the region for Lyme borreliosis, Borrelia miyamotoi infection, tick-borne encephalitis, human granulocytic anaplasmosis, rickettsiosis, neoehrlichiosis and babesiosis. The main conclusion is that the recommendations in these northern countries are essentially the same, with very few differences. This overview presents the current diagnostics and provides useful clinical guidance.
View Article and Find Full Text PDFThe impact of tick-borne diseases caused by pathogens such as Anaplasma phagocytophilum, Neoehrlichia mikurensis, Borrelia miyamotoi, Rickettsia helvetica and Babesia species on public health is largely unknown. Data on the prevalence of these pathogens in Ixodes ricinus ticks from seven countries within the North Sea Region in Europe as well as the types and availability of diagnostic tests and the main clinical features of their corresponding diseases is reported and discussed. Raised awareness is needed to discover cases of these under-recognized types of tick-borne disease, which should provide valuable insights into these diseases and their clinical significance.
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