Cholangiocyte organoids for disease, cancer, and regenerative medicine.

The biliary tract is a ductal network comprising the intrahepatic (IHBDs) and extrahepatic bile duct (EHBDs). Biliary duct disorders include cholangitis, neoplasms, and injury. However, the underlying mechanisms are not fully understood.

Electromigration-driven linear actuator operations of Co nanorods inside and outside multi-walled carbon nanotubes with stroke of tens of nanometers.

Solid Co nanorod fillers were pushed out of multi-walled carbon nanotubes electromigration and their behaviors were observed by transmission electron microscopy. When a solid Co nanorod was pushed out, the portion outside the nanotube increased in diameter. The behavior of the plastic deformation depended on the crystal orientation of the Co nanorod filler.

A Case of Severe Post-Biopsy Bleeding and Perforation in Gastric Amyloidosis.

We herein describe a case of severe post-biopsy bleeding and perforation in gastric amyloidosis. A 70-year-old man who had been on dialysis underwent esophagogastroduodenoscopy and biopsy was performed. Post-biopsy bleeding occurred, and three times of coagulation hemostasis and once clip hemostasis were performed.

Multi-frame blind deconvolution using X-ray microscope images of an in-plane rotating sample.

We propose a multi-frame blind deconvolution method using an in-plane rotating sample optimized for X-ray microscopy, where the application of existing deconvolution methods is technically difficult. Untrained neural networks are employed as the reconstruction algorithm to enable robust reconstruction against stage motion errors caused by the in-plane rotation of samples. From demonstration experiments using full-field X-ray microscopy with advanced Kirkpatrick-Baez mirror optics at SPring-8, a spatial resolution of 34 nm (half period) was successfully achieved by removing the wavefront aberration and improving the apparent numerical aperture.

A case of duodenal adenocarcinoma with a gastric phenotype demonstrating a rapidly progressive course.

We herein report a rare case of duodenal adenocarcinoma with a rapidly progressive course. Esophagogastroduodenoscopy revealed Brunner's gland hyperplasia in the bulbs of the duodenum three years prior to this presentation. Two years earlier, gastric foveolar metaplasia had been observed in the bulbs.