Comparative Study of Noncatheterized and Catheter-Associated Urinary Tract Infections by ESBL-Producing Gram-Negative Bacilli in an Urban Tertiary-Care Center, Salem, Tamil Nadu.

Background: Urinary tract infections are frequently caused by Gram-negative bacilli, and timely detection and management of resistant strains and their antimicrobial susceptibilities are crucial.

Methods: A six-month study examined Gram-negative bacilli from catheterized and noncatheterized patients, assessing antibiotic susceptibility, minimum inhibitory concentration, and Extended spectrum beta lactamase (ESBL) production genes using real-time Polymerase chain reaction (PCR).

Results: Out of 72 isolates, 55.

Prevalence of bla (CTX M) extended spectrum beta lactamase gene in enterobacteriaceae from critical care patients.

Context: Critical care units provide a favourable environment for the antimicrobial resistant organisms to disseminate. There is recent increase in number of extended spectrum beta lactamase (ESBL) producers because of the emergence of CTX M Beta lactamases produced by Enterobacteriaceae. They colonize the intestinal flora and spread with greater intensity in the community and hospital.