Objectives: Early childhood dental caries (ECC) is a prevalent dental condition affecting infants and young children, characterized by one or more carious lesions in primary teeth. ECC risk factors include malnutrition, genetic predisposition, specific dietary habits, lack of fluoride, and prolonged bottle feeding. A comprehensive prevalence estimate is crucial for understanding the extent of dental caries in the population.
View Article and Find Full Text PDFPurpose: This study aimed to select robust features against lung motion in a phantom study and use them as input to feature selection algorithms and machine learning classifiers in a clinical study to predict the lymphovascular invasion (LVI) of non-small cell lung cancer (NSCLC). The results of robust features were also compared with conventional techniques without considering the robustness of radiomic features.
Methods: An in-house developed lung phantom was developed with two 22mm lesion sizes based on a clinical study.
Bullous pemphigoid (BP) is the most common autoimmune-driven blistering disease. The incidence of BP has been rising due to population aging and exposure to medications such as biologics. Moreover, biologics are utilized as therapeutic choices for BP treatment as they inhibit cytokines and disrupt pathogenesis pathways.
View Article and Find Full Text PDFInt J Biol Macromol
March 2025
In the current study, gelatinized potato starch was modified by decanoyl chloride and curcumin via esterification and pH-driven method at two pH levels (pH 8 and 12), respectively, followed by precipitation and formation of anionic nanoparticles. The effects of modifications on the various properties of starch nanoparticles were investigated. A decrease in mean particle diameter and branching degree as well as an increase in product mass, fatty acid substitution degree (0.
View Article and Find Full Text PDFAlzheimer's disease (AD), which is caused by the accumulation of amyloid-beta, is a major medical concern today. Controlling these aggregates is critical to drug development, but delivering them effectively into the bloodstream poses significant challenges. In this context, aromatherapy has been proposed as an innovative and promising approach for AD disease.
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