Iranian early childhood dental caries: a comprehensive systematic review and meta-analysis of prevalence and associated risk factors.

Objectives: Early childhood dental caries (ECC) is a prevalent dental condition affecting infants and young children, characterized by one or more carious lesions in primary teeth. ECC risk factors include malnutrition, genetic predisposition, specific dietary habits, lack of fluoride, and prolonged bottle feeding. A comprehensive prevalence estimate is crucial for understanding the extent of dental caries in the population.

Robust vs. Non-robust radiomic features: the quest for optimal machine learning models using phantom and clinical studies.

Purpose: This study aimed to select robust features against lung motion in a phantom study and use them as input to feature selection algorithms and machine learning classifiers in a clinical study to predict the lymphovascular invasion (LVI) of non-small cell lung cancer (NSCLC). The results of robust features were also compared with conventional techniques without considering the robustness of radiomic features.

Methods: An in-house developed lung phantom was developed with two 22mm lesion sizes based on a clinical study.

A systematic review of the role of interleukin-17 inhibitors in bullous pemphigoid: therapeutic and paradoxical effects.

Bullous pemphigoid (BP) is the most common autoimmune-driven blistering disease. The incidence of BP has been rising due to population aging and exposure to medications such as biologics. Moreover, biologics are utilized as therapeutic choices for BP treatment as they inhibit cytokines and disrupt pathogenesis pathways.

Fabrication and characterization of decanoyl chloride/curcumin-modified potato starch nanoparticles and the potential application in the stabilization of flaxseed oil-in-water Pickering emulsions.

In the current study, gelatinized potato starch was modified by decanoyl chloride and curcumin via esterification and pH-driven method at two pH levels (pH 8 and 12), respectively, followed by precipitation and formation of anionic nanoparticles. The effects of modifications on the various properties of starch nanoparticles were investigated. A decrease in mean particle diameter and branching degree as well as an increase in product mass, fatty acid substitution degree (0.

The Use of Natural Volatile Compounds on the Fibrillation Domain of Amyloid Beta (GSNKGAIIGLM)─Towards Promising Agents to Combat Alzheimer's Disease.

Alzheimer's disease (AD), which is caused by the accumulation of amyloid-beta, is a major medical concern today. Controlling these aggregates is critical to drug development, but delivering them effectively into the bloodstream poses significant challenges. In this context, aromatherapy has been proposed as an innovative and promising approach for AD disease.