Publications by authors named "S Martinenghi"
Article Synopsis
- Insulin resistance is an important factor in the early stages of type 1 diabetes (T1D) risk, and the study looks at its genetic, metabolic, and immune aspects among at-risk individuals.
- Researchers divided relatives of T1D patients into high and low insulin resistance groups and assessed their genetic risk, glucose control, metabolic hormones, and immune cell profiles.
- The high insulin resistance group showed metabolic changes like increased insulin levels and a unique immune cell profile with more insulin-specific CD8 T cells, suggesting a link between insulin resistance and immune responses in T1D susceptibility.
Coronavirus disease 2019 (COVID-19) may lead to neuropsychiatric sequelae. Palmitoylethanolamide (PEA) is an anti-inflammatory and neuroprotective amide used in depressive syndromes. Here we investigate whether micronized/ultramicronized (m/um) PEA improves neuropsychiatric sequelae in COVID-19 survivors.
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- Post-COVID-19 syndrome can affect patients differently, regardless of initial disease severity or health status, with frailty potentially influencing long-term symptoms.
- An observational study tracked 382 patients aged 65+ after hospitalization for COVID-19 pneumonia, revealing frail individuals had worse nutritional and physical health outcomes compared to more robust patients.
- Key findings included frailty being linked to increased confusion, malnutrition, impaired mobility, and respiratory issues one month post-discharge.
Objective: To report a preliminary experience of outpatient management of patients with Coronavirus disease 2019 (COVID-19) through an innovative approach of healthcare delivery.
Patients And Methods: Patients evaluated at the Mild-to-Moderate COVID-19 Outpatient clinics (MMCOs) of San Raffaele University Hospital and Luigi Sacco University Hospital in Milan, Italy, from 1 October 2020 to 31 October 2021 were included. Patients were referred by general practitioners (GPs), Emergency Department (ED) physicians or hospital specialists (HS) in case of moderate COVID-19.
Background: Persistent symptoms including dyspnea and functional impairment are common in COVID-19 survivors. Poor muscle quality (myosteatosis) associates with poor short-term outcomes in COVID-19 patients. The aim of this observational study was to assess the relationship between myosteatosis diagnosed during acute COVID-19 and patient-reported outcomes at 6 months after discharge.
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