Publications by authors named "S Marinou"
SARS-CoV-2 infections in children are generally asymptomatic or mild and rarely progress to severe disease and hospitalization. Why this is so remains unclear. Here we explore the potential for protection due to pre-existing cross-reactive seasonal coronavirus antibodies and compare the rate of antibody decline for nucleocapsid and spike protein in serum and oral fluid against SARS-CoV-2 within the pediatric population.
View Article and Find Full Text PDFObjective: To understand community seroprevalence of SARS-CoV-2 in children and adolescents. This is vital to understanding the susceptibility of this cohort to COVID-19 and to inform public health policy for disease control such as immunisation.
Design: We conducted a community-based cross-sectional seroprevalence study in participants aged 0-18 years old recruiting from seven regions in England between October 2019 and June 2021 and collecting extensive demographic and symptom data.
Article Synopsis
- A study was conducted on UK healthcare workers from April to June 2020 to explore how acquired immunity to COVID-19 develops, particularly before vaccines were available.
- The researchers found that immune responses to the virus varied widely among participants, with some immune markers decreasing over time while others remained stable.
- A subgroup of individuals displayed stronger immune responses, which correlated with long-term protection against severe disease from COVID-19 and its variants.