Publications by authors named "S Margulies"

Infantile perianal pyramidal protrusion is characterized by a light pink to skin-colored soft tissue protrusion that is often midline and anterior [A1]to the anus. It most commonly occurs in young females and is relatively asymptomatic. Although biopsies are not routinely done, histopathology is relatively nonspecific and can appear similar to an acrochordon.

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Article Synopsis
  • Sports-related concussions often lead to cognitive issues, especially in younger individuals, although most symptoms resolve within a week.
  • This study utilized a swine model to analyze how single and repeated head rotations affect brain activity (measured by rs-EEG) in piglets during the first week post-injury.
  • Results showed that healthy piglets displayed stable brain activity metrics, while repeated head rotations led to a temporary increase in alpha power on the first day post-injury, indicating potential changes in brain function.
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Background: Chronic red blood cell (RBC) transfusion is an established therapy to prevent stroke in patients with sickle cell anemia (SCA). It is unclear if adding daily hydroxyurea treatment to chronic transfusion is beneficial.

Study Design And Methods: We conducted a phase 2 clinical trial (NCT03644953) investigating the addition of dose-escalated hydroxyurea to chronic transfusion for patients with SCA receiving simple chronic transfusion for stroke prevention.

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Importance: The Neomedic Knotless Incontinence Mesh (KIM) sling with sterilizable trocars decreases medical waste versus midurethral slings with disposable trocars. Limited comparative data exist.

Objective: The aim of the study was to assess to the success of the retropubic KIM sling compared to the Gynecare TVT Exact sling.

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Background: Children aged 0-4 years have the highest rate of emergency department (ED) visits for traumatic brain injury (TBI); falls are the leading cause. Infants younger than 2 years are more likely to sustain a fractured skull after a fall.

Objective: This study examined caregiver actions and products associated with ED visits for fall-related fractured skulls in infants aged 0-4 months.

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