Publications by authors named "S Marciani Magno"
: B3 breast lesions, characterized by uncertain malignant potential, pose a significant challenge for clinicians. With the increasing use of preoperative biopsies, there is a need for careful management strategies, including watchful waiting, vacuum-assisted excision (VAE), and surgery. This study aims to assess the concordance between preoperative biopsy findings and postoperative histology, with a focus on evaluating the positive predictive value (PPV) for malignancy in B3 lesions.
View Article and Find Full Text PDFPurpose: Neoadjuvant chemotherapy (NAC) has a well-established role in locally advanced or chemoresponsive breast cancers (BC). Chemotherapic regimens are effective when patients receive the optimal doses. Toxicities are common in overweight/obese patients but may occur also in normal weight counterparts.
View Article and Find Full Text PDFBreast cancer stands as the most frequently diagnosed cancer and the primary cause of cancer-related mortality among women worldwide, including Italy. With the increasing number of survivors, many are enrolled in regular follow-up programs. However, adherence to recommendations from scientific societies (such as ASCO, ESMO, AIOM) for breast cancer follow-up management varies in daily clinical practice across different cancer centers, potentially resulting in unequal management and escalating costs.
View Article and Find Full Text PDFHaematogenous polyostotic osteomyelitis caused by Serratia marcescens in a cat.
Top Companion Anim Med
December 2024
Article Synopsis
- A 2-year-old Bengal cat experienced sudden lameness in her right forelimb a month after surgery for spaying, leading to further investigation.
- Tests revealed severe bone infection caused by a drug-resistant strain of Serratia marcescens, prompting a two-month course of targeted antibiotics.
- The cat's lameness and bone pain improved rapidly, and by the six-month follow-up, she had fully recovered, with only minor bone changes visible on X-rays.
Background: Neoadjuvant chemotherapy (NAC) is delivered before surgery to allow less extensive tumour resection, but the optimal surgical margin width after NAC is unknown. The aim of this study was to determine the impact of reassigned margins on local recurrence after NAC in dogs with mast cell tumours (MCTs).
Methods: A retrospective analysis was conducted for dogs with MCTs undergoing NAC consisting of vinblastine and prednisolone, subsequent tumour resection and lymphadenectomy, and a minimum follow-up of 6 months.