Publications by authors named "S Maples"
Article Synopsis
- - The study investigates the impact of melphalan dosing and chronic kidney disease (CKD) on outcomes in multiple myeloma patients undergoing autologous stem cell transplantation (ASCT), addressing the lack of standard renal dose adjustments.
- - Researchers assessed 124 patients (108 without CKD and 16 with CKD), evaluating metrics such as progression-free survival (PFS), overall survival (OS), and complications, using statistical methods for analysis.
- - Results indicated that while the CKD group had a median PFS of 60 months compared to 46 months for no-CKD patients, there was a notable increase in severe mucositis in the CKD group, highlighting the need for tailored treatment approaches based
Objective: To identify determinants of intended versus actual care-seeking behaviours in a pluralistic healthcare system that is reliant on both conventional and non-conventional providers and discover opportunities to catalyse improved healthcare access.
Design: Cross-sectional study.
Setting And Participants: In Haiti 568 households (incorporating 2900 members) with children less than 5 years of age were randomly sampled geographically with stratifications for population density.
Background: Diarrheal disease is a leading cause of morbidity and mortality globally, especially in low- and middle-income countries. High-throughput and low-cost approaches to identify etiologic agents are needed to guide public health mitigation. Nanoliter-qPCR (nl-qPCR) is an attractive alternative to more expensive methods yet is nascent in application and without a proof-of-concept among hospitalized patients.
View Article and Find Full Text PDFBackground: Acute diarrhoeal disease management often requires rehydration alone without antibiotics. However, non-indicated antibiotics are frequently ordered and this is an important driver of antimicrobial resistance. The mHealth Diarrhoea Management (mHDM) trial aimed to establish whether electronic decision support improves rehydration and antibiotic guideline adherence in resource-limited settings.
View Article and Find Full Text PDFBackground: Implementation of population-based surveys is resource intensive and logistically demanding, especially in areas with rapidly changing demographics and incomplete or no enumeration of the underlying population and their residences. To remove the need for pre-enumeration and to simplify field logistics for the population healthcare utilization survey used for the Surveillance for Enteric Fever in Asia Project in Nepal, we incorporated a geographic information system-based geosurvey and field mapping system into a single-stage cluster sampling approach.
Methods: A survey was administered to ascertain healthcare-seeking behavior in individuals with recent suspected enteric fever.