Public Health.

Background: Life-course food insecurity may influence cognition through pathways of stress and poor health. Yet, few longitudinal studies examine whether life-course food insecurity is associated with cognition among U.S.

Dementia Care Research and Psychosocial Factors.

Background: Black, Latinx, and Asian community elders remain underrepresented in dementia research. This study explored whether a video created to promote diversity in research by featuring underrepresented ADRC participants would change attitudes about research generally (e.g.

Angiotensin II type-1 receptor autoantibodies and effects in neonates of women with preeclampsia.

Background: Maternal agonistic autoantibodies against the angiotensin II type 1 receptor (AT1-AAs) have been implicated in the pathophysiology of preeclampsia, but their presence in their offsprings and their possible neonatal effects have not been specifically explored. This prospective study aimed to evaluate the presence of AT1-AAs and their potential clinical effects in neonates of AT1-AAs positive mothers.

Methods: Women with preeclampsia and their neonates were included.

Resazurin dye is an in vivo sensor of kidney tubular function.

Glomerular filtration rate (GFR) is the main functional index of kidney health and disease. Currently, no methods are available to directly measure tubular mass and function. Here, we report a serendipitous finding that the in vitro cell viability dye resazurin can be used in mice as an exogenous sensor of tubular function.

Pleozymes: Pleiotropic Oxidized Carbon Nanozymes Enhance Cellular Metabolic Flexibility.

Our group has synthesized a pleiotropic synthetic nanozyme redox mediator we term a "pleozyme" that displays multiple enzymatic characteristics, including acting as a superoxide dismutase mimetic, oxidizing NADH to NAD, and oxidizing HS to polysulfides and thiosulfate. Benefits have been seen in acute and chronic neurological disease models. The molecule is sourced from coconut-derived activated charcoal that has undergone harsh oxidization with fuming nitric acid, which alters the structure and chemical characteristics, yielding 3-8 nm discs with broad redox potential.