Multiple sclerosis (MS) is a disease of the central nervous system, characterized by progressive demyelination and inflammation. MS is characterized by immune system attacks on the myelin sheath surrounding nerve fibers. Genome-wide association studies revealed a polymorphism in the signal transducer and activator of transcription 4 (STAT4) gene that increases risk for MS.
View Article and Find Full Text PDFBackground: In the realm of system biology, it is a challenging endeavor to infer a gene regulatory network from time-series gene expression data. Numerous Boolean network inference techniques have emerged for reconstructing a gene regulatory network from a time-series gene expression dataset. However, most of these techniques pose scalability concerns given their capability to consider only two to three regulatory genes over a specific target gene.
View Article and Find Full Text PDFThe indigenous community in Malaysia also known as Orang Asli have preserved their unique cultural identity in the face of rapid national development and modernization efforts. Over the years, poverty alleviation has become a central pillar of Malaysia development. In this review, seroprevalence report from the Orang Asli and their health status about neglected tropical diseases were collated and analyzed.
View Article and Find Full Text PDFAgriculture plays a vital role in Bangladesh's economy. It is essential to ensure the proper growth and health of crops for the development of the agricultural sector. In the context of Bangladesh, crop diseases pose a significant threat to agricultural output and, consequently, food security.
View Article and Find Full Text PDFObjectives: Gunshot injuries have become a significant problem globally. This study aimed to assess the differences between abdominal versus pelvic gunshot injuries in terms of postoperative outcomes to determine which type of injury is more lethal.
Material And Methods: This was a cohort study carried out to compare patients who had abdominal versus pelvic gunshot injuries, to analyse the differences in the impact of the anatomical site of injury on morbidity, mortality, and disabilities in all patients who had been admitted to the hospital due to torso gunshot injuries from February 2011 to December 2018.