Brightness and AIEE behaviour of methylenebis(4,1-phenylene) linkage electron donor-acceptor-based dyads and their implications for robust quantification of explosive picric acid in both aqueous medium and solid state.

Organic luminescent materials having photoluminescence in their solid state have become emerging trends in chemistry, materials science, and biology due to their versatile potential applications. In the present contribution, we have introduced some methylenebis(4,1-phenylene) electron donor-acceptor-based fashionable solid-state fluorescent molecules, MBA, MBB, and MBH, having exciting photoluminescence characteristics in their solid and aggregate states. Interestingly, all probes exhibited a compelling aggregation-induced enhanced emission (AIEE) phenomenon in aqueous media.

Effect of fathers in Preemie Prep for Parents (P3) program on couple's preterm birth preparedness.

Objective: Evaluate the effect of fathers' participation in the Preemie Prep for Parents (P3) program on maternal learning and fathers' preterm birth knowledge.

Methods: Mothers with preterm birth predisposing medical condition(s) enrolled with or without the baby's father and were randomized to the P3 intervention (text-messages linking to animated videos) or control (patient education webpages). Parent Prematurity Knowledge Questionnaire assessed knowledge, including unmarried fathers' legal neonatal decision-making ability.

Identifying Medical Concepts and Semantic Types in Lay Vocabularies of Health Consumers Who are Concerned with Diabetes on Social Media Using the UMLS and NLP.

This study suggests a way to utilize the existing medical ontology and natural language processing techniques to extract major medical concepts from lay vocabularies of health consumers on social media and group them based on the defined semantic types in the ontology. Diabetes-related discussions on Tumblr was used to test the efficiency of SpaCy and the Markov-Viterbi algorithm to map lay medical terms to the defined medical concepts in the UMLS. The system discussed in this paper can better analyze free texts, take care of word ambiguity and extract the lifestyle indicators from the daily life discussions of diabetic people on Tumblr.

Ni(0)-Catalyzed Efficient, Regioselective Synthesis of Dibenzo[,]oxepines and Dibenzo[,][1,2]oxathiepine 6,6-Dioxides: Mechanistic Study by DFT Calculation and Docking Interactions.

Herein, a nickel-catalyzed divergent reductive-Heck reaction of 1-bromo-2-((2-(aryl/alkyl ethynyl)phenoxy)methyl)benzene and 2-(aryl/alkyl ethynyl)phenyl 2-bromobenzenesulfonate derivatives has been demonstrated through the regulation of reducing agents and solvent systems. This scalable protocol offers regio- and stereoselective access to functionalized dibenzo[,]oxepine and dibenzo[,][1,2]oxathiepine 6,6-dioxide scaffolds in high to excellent yields under a mild set of reaction conditions. This methodology offers a predictable route for the synthesis of medium ring oxygen heterocycles and demonstrates wide substrate scope and outstanding tolerance to various functional groups like hydroxyl and, of course, practical instance via the synthesis of doxepin and nordoxepin molecules.