Publications by authors named "S Malak"

Article Synopsis
  • Acquired resistance to cisplatin, a common treatment for ovarian cancer, presents significant challenges in therapy effectiveness, leading researchers to identify a new phenomenon in cancer cell behavior.
  • This study introduces the concept of epithelial-mesenchymal-ectodermal transition (EMET), which describes how ovarian cancer cells undergo a transformation that includes characteristics of neuronal differentiation and stemness, indicating a shift in their cellular identity.
  • The researchers also found that a small population of these cancer cells, which exhibit both neuronal-like features and multidrug resistance, likely originate from neural cells, suggesting that ovarian cancer may arise from a neuroepithelial lineage.
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Early detection of breast cancer from regular screening substantially reduces breast cancer mortality and morbidity. Multiple different imaging modalities may be used to screen for breast cancer. Screening recommendations differ based on an individual's risk of developing breast cancer.

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Background: To date, there remains a paucity of present-day literature on the topic of demographics and the biopsy-proven pathological positivity rate of endometriosis.

Objective: The goal of this study was to explore the association between patients' demographics and other concomitant gynecological conditions or procedures and the pathological positivity rate of excision of endometriosis.

Design: Retrospective cohort study.

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Objective: To determine the feasibility of standardized, prospective assignment of initial method of detection (MOD) of breast cancer by radiologists in diverse practice settings.

Methods: This multicenter, retrospective study analyzed the rate of assignment of MOD in four geographically varied health systems. A universal protocol for basic MOD assignment was agreed upon by the authors before start of the pilot study.

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Where someone lives is a major determinant of population health. In the United States, people who live in Health Professional Shortage Areas are considered medically underserved and have a higher propensity for conditions such as stroke, hypertension, and diabetes. Our goal was to better understand the diverse needs of patients presenting to the Crouse Hospital emergency department with stroke symptoms.

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