Ethnic variations in the haemostatic system: comparison between Arabs, Westerners (Europeans and Americans), Asians and Africans.

A wide variety of haemostatic variables were measured in healthy male subjects predominantly blood donors residing in Riyadh, the capital city of Saudi Arabia. Subjects were divided according to ethnic origin: Saudi Arabs n = 487, Westerners (Europeans and Americans) n = 300, South East Asians (Koreans and Filipinos) n = 360, and West Africans n = 82. There were no significant differences in prothrombin time, partial thromboplastin time, thrombin time, reptilase time, plasma fibrinogen, antithrombin, plasminogen and platelet count between Saudis, Westerners and Asians.

Hemostatic changes following surgery.

Measurements of hemostatic variables were performed prior to and up to the fifth day following general surgery in patients of Arab origin (N = 53). There was a significant postoperative elevation in the levels of plasma fibrinogen, clotting factors VIII and reduction of factor VII, ATIII, plasminogen, packed cell volume and platelet count. No significant changes were noted in PT, PTT, TT, RT, alpha-2-antiplasmin and factor X.

Ethnic variations in platelet aggregation-comparison between saudi arabs, westerners (europeans and americans), asians and africans.

SUMMARY. Platelet aggregation responses to adenosine diphosphate, adrenaline, collagen, arachidonic acid and ristocetin were measured in healthy subjects, predominantly blood donors residing in Riyadh, the capital city of Saudi Arabia. They were divided according to ethnic origin into Saudi Arabs n = 517, Westerners (Europeans and Americans) n = 93, South East Asians (Koreans and Filipinos) n = 154, and West Africans n = 77.

A Study of the Normal Pattern of Platelet Aggregation in Healthy Saudis: A Population-based Study.

Platelet aggregation in response to ADP, adrenaline, collagen, arachidonic acid and ristocetin was measured in a large population of healthy Saudi males (n = 393) and females (n = 221) whose age ranged from 11-60 years. The number of observations ranged from 130 for one of the doses of ristocetin (1.0 g/l) to 554 for one of the doses of ADP (2.