Publications by authors named "S Maegawa"
Osteosarcoma is a primary malignant bone tumor. Effective chemotherapy regimens for refractory disease are scarce, accounting for no improvement in survival. Immune-based cell therapies have emerged as novel alternatives.
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- Fanconi anemia (FA) is a hereditary disorder caused by mutations in the FA pathway, leading to developmental issues, bone marrow failure, and a higher risk of cancer due to impaired DNA repair mechanisms related to formaldehyde-induced damage.
- Researchers created a zebrafish model of FA by disrupting certain genes, which displayed abnormal sex characteristics and reduced fertility; the addition of the ADH5 enzyme showed potential for improving sperm development.
- The study suggests that enhancing ADH5 activity could be a promising therapeutic approach for managing formaldehyde toxicity and treating FA.
Tooth shade determination methods for evaluating the effectiveness of whitening products at home are limited. In this study, an iPhone app for personalized tooth shade determination was developed. While capturing dental photographs in selfie mode before and after whitening, the app can maintain consistent illumination and tooth appearance conditions that affect tooth color measurement.
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