Olanzapine for young PEople with aNorexia nervosa (OPEN): results of a feasibility study.

Background: Despite the availability of evidence-based treatments for anorexia nervosa (AN), remission rates are moderate, and mortality is high. Olanzapine is used as adjunct therapy for AN in case of insufficient response to first-line treatments, even though the evidence is limited. Its effect on eating disorder (ED) psychopathology, its efficacy and tolerability, and its acceptability and adherence rate are unclear.

Unveiling Factors Influencing Mortality in Irish Hip Fracture Patients: A Comprehensive Five-Year Analysis.

Background: Hip fractures impose a substantial healthcare burden, contributing to increased morbidity, disability, and mortality. The Irish Hip Fracture Standards (IHFS) were officially employed in 2017, providing specialized pathways for hip fracture care to improve patient outcomes. This study evaluated the performance of our unit regarding hip fracture care and analyzed individual outcome parameters.

A screen for cell envelope stress uncovers an inhibitor of prolipoprotein diacylglyceryl transferase, Lgt, in .

The increasing prevalence of antibiotic resistance demands the discovery of antibacterial chemical scaffolds with unique mechanisms of action. Phenotypic screening approaches, such as the use of reporters for bacterial cell stress, offer promise to identify compounds while providing strong hypotheses for follow-on mechanism of action studies. From a collection of ∼1,800 GFP transcriptional reporter strains, we identified a reporter that is highly induced by cell envelope stress-pProm -GFP.

Behavioral assessment and treatment of pica: a brief report.

Pica is a life-threatening behavior that is relatively common among individuals with intellectual and developmental disabilities. Pica can be conceptualized as a response chain in which the pica item acts as a discriminative stimulus for the next response (i.e.

The Relationship of a Predictable Ability Measurement Examination and NCLEX-RN Disposition.

Background: End-of-program examinations have been used to determine nursing students' readiness for the National Licensure Examination for Registered Nurses (NCLEX-RN). The Clinical Judgment Registered Nurse Readiness Examinations (CJE-RN REs) have been adopted by nursing schools for the last 5 years.

Purpose: The purpose of this study was to validate the use of the CJE-RN REs by examining the relationship with first-time pass rates among nursing students.