Background: The prevalence of chronic kidney disease (CKD) is estimated to be about 13.4% worldwide. Studies have shown that CKD accounts for up to 2% of the health cost burden.
View Article and Find Full Text PDFPurpose: To assess the utility of volumetric tumor enhancement on CT to predict tumor treatment response and the overall survival (OS) of patients with PDAC undergoing FOLFIRINOX-based systemic chemotherapy. Additionally, we aim to explore the performance of a novel model that incorporates relevant volumetric CT-derived parameters to the established RECIST 1.1 in predicting both treatment response and OS.
View Article and Find Full Text PDFComput Methods Programs Biomed
February 2025
Background: Mixed-reality-assisted surgery has become increasingly prominent, offering real-time 3D visualization of target anatomy such as tumors. These systems facilitate translating preoperative 3D surgical plans to the patient's body intraoperatively and allow for interactive modifications based on the patient's real-time conditions. However, achieving sub-millimetre accuracy in mixed-reality (MR) visualization and interaction is crucial to mitigate device-related risks and enhance surgical precision.
View Article and Find Full Text PDFIn modern analytical chemistry, one of the primary goals is to develop miniaturized, easy-to-use sensing tools, particularly those with multitasking capabilities. In this work, we designed a mini-voltammetric cell that integrates a modified Au microelectrode (Au/Au NPs as the working electrode) and an Ag/AgCl reference electrode installed within a micropipette tip. This combined tool not only enables portable and on-site microvolume sampling─requiring only a microvolume (around 20-40 μL) or a single droplet─but also facilitates direct micro-electroanalysis in a short time.
View Article and Find Full Text PDFBackground: Although kidney diseases have a high prevalence, initial recognition and diagnosis of renal disease are complicated in avian medicine.
Objective: The aim of this study is to assess the intraosseous excretory urography (IOEU) in order to introduce a new method for evaluation of kidney's function in broilers as a primary model of birds.
Methods: A total of 10 male broiler chickens at the age of 20 days were included and evaluated with plain and serial post-contrast radiography and computed tomography (CT) scan to check the time and concentration of the contrast media (CM) passage from the kidney.