Young-onset diabetes in Asian Indians is associated with lower measured and genetically determined beta cell function.

Aims/hypothesis: South Asians in general, and Asian Indians in particular, have higher risk of type 2 diabetes compared with white Europeans, and a younger age of onset. The reasons for the younger age of onset in relation to obesity, beta cell function and insulin sensitivity are under-explored.

Methods: Two cohorts of Asian Indians, the ICMR-INDIAB cohort (Indian Council of Medical Research-India Diabetes Study) and the DMDSC cohort (Dr Mohan's Diabetes Specialties Centre), and one of white Europeans, the ESDC (East Scotland Diabetes Cohort), were used.

Modified technique for unipolar allograft ankle replacement: midterm follow-up. A case report.

The management of tibiotalar arthritis remains a clinical challenge. Conventional treatment relies primarily upon arthrodesis or prosthetic arthroplasty. Fresh osteochondral total ankle allograft transplantation has been reported in limited cases.

Survey of short-term oral corticosteroid administration by orthopaedic physicians in college and high school athletes.

The use of oral corticosteroid (OCS) drugs is advocated because of their potent anti-inflammatory effects. They also possess many potential adverse effects. No study has assessed physician prescribing practices of OCS therapy in high school (HS) or college (COL) athletes.

Osteoarticular autograft and allograft transplantation of the knee: 3 year follow-up.

Between 1998 and 2001, a total of 48 patients underwent autologous or allograft osteoarticular transplantation with a minimum follow-up of 24 months. Nineteen patients underwent concomitant procedures. Average patient age was 46 years.