Publications by authors named "S MARTON"
Avian pox is a globally spread viral disease affecting a wide spectrum of wild and domesticated bird species. The disease is caused by a diverse group of large DNA viruses, namely, avipoxviruses (genus , family ). In this study, gross pathological examination and histopathological examination of skin lesions and several organs suggested acute poxvirus infection of a Eurasian crane (, Linnaeus, 1758).
View Article and Find Full Text PDFMycoplasma (M.) hyosynoviae is a facultative pathogen, causing arthritis in finisher pigs world-wide. In the absence of a commercial vaccine improvement of housing conditions and antibiotic therapy are the only options to alleviate the clinical signs.
View Article and Find Full Text PDFThe aim of this study was to evaluate how COVID-19 affected acute stroke care and outcome in patients with acute ischemic or hemorrhagic stroke. We performed a retrospective analysis on patients who were admitted with acute ischemic (AIS) or hemorrhagic (ICH) stroke from September 2020 to May 2021 with and without COVID-19. We recorded demographic and clinical data, imaging parameters, functional outcome and mortality at one year.
View Article and Find Full Text PDFArticle Synopsis
- Three types of small RNA therapeutics—siRNAs, miRNAs, and ASOs—have advantages over traditional drugs by targeting gene products, offering new treatment avenues for various diseases.
- While these small RNAs are valuable in preclinical research for gene silencing and drug target validation, off-target effects, particularly miRNA-like ones, can complicate results and lead to adverse effects.
- The review discusses strategies such as sequence design and AI-based predictions to minimize these off-target effects, providing a comprehensive overview of current computational methods and experimental validation techniques to support small RNA therapy development.
Objective: Our aim was to examine the significance of single-fiber electromyography (SFEMG) in patients diagnosed with amyotrophic lateral sclerosis (ALS) and determine the best correlating parameter with SFEMG parameters and clinical scales across different muscles including facial muscles.
Methods: SFEMG examinations were conducted on the extensor digitorum (ED), frontalis, and orbicularis oculi muscles. Mean jitter, percentage of increased jitter, fiber density (FD), and impulse blocking percentage were compared to reference values and functional scales.