Publications by authors named "S M Von"
Frequent plateletpheresis is associated with severe lymphopenia of uncertain clinical significance. We assessed the functional impact of frequent platelet donations and associated lymphopenia on the response to neoantigens. We conducted a prospective study of 102 platelet donors (HIV uninfected) who were naive to meningococcal vaccination recruited at Brigham and Women's Hospital.
View Article and Find Full Text PDFArticle Synopsis
- Phocaeicola vulgatus is a common bacterium in the human gut that produces a newly discovered antibacterial protein called BcpT, which is encoded on a mobile plasmid.
- BcpT needs to be cleaved at two specific sites to become active, and certain bacterial proteases are responsible for this activation.
- This toxin targets other bacteria by recognizing a specific receptor, leading to stress responses that prompt the expression of protective genes against various antimicrobial agents.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins were measured in longitudinal plasma samples collected from 13 participants who received two doses of mRNA-1273 vaccine. Eleven of 13 participants showed detectable levels of SARS-CoV-2 protein as early as day 1 after first vaccine injection. Clearance of detectable SARS-CoV-2 protein correlated with production of immunoglobulin G (IgG) and immunoglobulin A (IgA).
View Article and Find Full Text PDFArticle Synopsis
- Adult women with long-term anorexia nervosa (AN) show high rates of osteopenia and osteoporosis, but a study suggests that their bone microarchitecture, measured using Trabecular Bone Score (TBS), is only moderately compromised.
- The research involved 20 female patients with AN who had their bone density and turnover markers compared to healthy controls, revealing altered serum levels of bone turnover markers like osteopontin.
- Results indicated that while 65% of patients had reduced bone mineral density (BMD), only 5% experienced fractures, indicating a lower-than-expected level of bone deterioration in this population.
Switchable cool and cold white emission from dysprosium doped SrZnO.
J Phys Condens Matter
September 2020
In presented work, excitation selective novel cool and cold white emission is reported from dysprosium (Dy) doped SrZnOnanophosphors, synthesized by combustion technique. The host lattice provided selective excitation routes for Dylevels and intrinsic defects levels via charge transfer (270 nm) and host defects absorption bands (375 nm), respectively. The emission due to Dylevels was found to be exhibiting cool white emission and that from intrinsic defects was cold white emission, as characterized from correlated color temperature.
View Article and Find Full Text PDF