Added diagnostic performance of diffusion-weighted imaging for differentiating malignant from benign gallbladder lesions: a systematic review with meta-analysis.

Background: Gallbladder malignancies, especially gallbladder cancer, are aggressive lesions with a poor prognosis, and correct differentiation from benign lesions is crucial for improved outcomes. Recently, diffusion-weighted imaging (DWI) has demonstrated potential for this aim to evaluate suspicious lesions detected by initial imaging (e.g.

The role of methylation quantification of circulating tumor DNA (ctDNA) as a diagnostic biomarker of Pheochromocytomas (PCCs) and Paragangliomas (PGLs).

Objectives: Circulating tumor DNAs (ctDNAs) are fragments of malignant tissue DNA that can simply signify the real time genetic change and epigenetic modification of a solid tumor tissue. Pheochromocytomas (PCCs) and Paragangliomas (PGLs) are malinancy of adrenal gland tissue that have the possible diagnosis by ctDNAs. In this study the methylation quanifcation of three target genes , , and in the ctDNA of PCCs/PGLs patients were measured as a diagnostic biomarker.

Surgical versus non-surgical management of hyperfunctional thyroid metastasis: a case report.

Background: Hyperthyroidism, caused by metastatic differentiated thyroid cancer, is a rare condition that can be difficult to diagnose. Thyrotoxicosis and metastatic disease regarding functional metastasis increase morbidity and mortality in patients with functional metastasis and need to be treated. This study aims to present a case of hyper-functional metastasis of thyroid cancer to analyze its pathological features, diagnostic procedures, and treatment options and to gather and examine recent cases of hyper-functional metastasis of thyroid cancer.

Unusual Presentation of Metastatic Medullary Thyroid Cancer Involving Bone Marrow, Kidneys, and Adrenal Gland: A Literature Review Based on a Case Report.

Background: Medullary thyroid cancer (MTC) is one of the rare neuroendocrine malignancies. This cancer is hereditary in approximately 20% of cases. Although lymph node (LN) metastasis is prevalent in MTC, distant metastasis is not commonly seen in these patients.