Publications by authors named "S M Sedaghat"

Background: Soft-tissue sarcomas are rare tumors of the soft tissue. Recent diagnostic studies mainly dealt with conventional image analysis and included only a few cases. This study investigated whether low- and high-proliferative soft tissue sarcomas can be differentiated using conventional imaging and radiomics features on MRI.

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Background: Breast cancer management depends on molecular subtypes. The aim was to compare disease-free survival (DFS) among the different subgroups. Overall survival (OS) is a secondary endpoint.

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  • Coagulation factor XI (FXI) inhibitors show potential as new anticoagulants but may worsen heart failure and diastolic dysfunction according to an animal study.
  • In the ARIC study, involving 4,471 older participants, researchers found that lower plasma FXI levels were linked to a higher incidence of heart failure over a median follow-up of 9 years, especially in those aged 75 and older.
  • The study also noted that while lower FXI levels were associated with increased prevalence of diastolic dysfunction, they correlated with a higher likelihood of atrial fibrillation at the baseline, but not with new cases of atrial fibrillation during the follow-up.
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  • The study focuses on the increasing incidence of pancreatic cancer (PC) in Golestan province, Iran, highlighting its poor prognosis and rising mortality rates over the last 25 years.
  • Patient data from the Golestan Population-Based Cancer Registry between 2006 and 2019 was analyzed, revealing that the age-standardized incidence rate (ASR) of PC is significantly higher in males and urban areas compared to females and rural areas.
  • Results indicated the ASR of PC increased from 1.97 to 3.53 per 100,000 persons-year, with an estimated annual percentage change (EAPC) of 4.39%, suggesting a concerning upward trend in PC cases, especially among men and the elderly
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: This study aims to investigate MRI features predicting the grade of STS malignancy using conventional image reading and radiomics. : Pretherapeutic imaging data regarding size, tissue heterogeneity, peritumoral changes, necrosis, hemorrhage, and cystic degeneration were evaluated in conventional image reading. Furthermore, the tumors' apparent diffusion coefficient (ADC) values and radiomics features were extracted and analyzed.

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