Publications by authors named "S M Sattler"
Autism Spectrum Disorders (ASD) are a set of neurodevelopmental disorders with complex biology. The identification of ASD risk genes from exome-wide association studies and de novo variation analyses has enabled mechanistic investigations into how ASD-risk genes alter development. Most functional genomics studies have focused on the role of these genes in neurons and neural progenitor cells.
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- Telangiectasia is a key feature of rosacea, necessitating effective treatment and standardized assessment tools for clinical evaluations.
- The study aimed to create and validate the TRoSA scale, a five-point photonumeric system to evaluate telangiectasia severity in rosacea patients, using feedback from 16 experts and 50 patient images.
- Results showed that the TRoSA scale has high interrater and intrarater reliability, making it a reliable tool for consistent clinical assessments and treatment evaluations in rosacea.
Background: In ventricular tachycardia (VT), optimal substrate mapping strategies identifying arrhythmogenic sites are not established.
Objectives: This study sought to evaluate multidirectional pacing on the distribution of specific conduction and repolarization metrics to localize re-entrant VT sites in a porcine infarct model.
Methods: Substrate maps were created in 13 pigs with chronic myocardial infarction using the Advisor HD Grid (Abbott) during right ventricular (RV), left ventricular, biventricular pacing (BIV), and sinus rhythm (SR).
Coronary artery disease (CAD) is a major health issue. This study focused on pericardial macrophages and small extracellular vesicles (sEVs) in CAD. The macrophages in CAD patients showed reduced expression of protective markers and unchanged levels of proinflammatory receptors.
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