Publications by authors named "S M Sami"
Article Synopsis
- The article "Health Related Quality of Life After Neonatal Treatment of Symptomatic Tetralogy of Fallot" is praised for its significant contributions to the field of pediatric cardiology.
- However, it has limitations, including a small sample size that affects the general applicability of its findings and a need for more research on comorbidities influencing health-related quality of life (HRQOL).
- The absence of a control group and the necessity for longer follow-up periods to track ongoing challenges faced by children post-treatment are highlighted as areas for improvement to enhance understanding of HRQOL in this patient population.
Aim: This study aimed to describe self-assessed clinical gerontological nursing competence and its associated factors among licensed practical nurses.
Design: A descriptive cross-sectional design was adopted for the study.
Methods: Data were collected in Autumn 2023 from 394 licensed practical nurses working in healthcare services for older people in one well-being services county in Finland.
Article Synopsis
- This study explores how (poly)phenols, particularly from grape and blueberry extracts (Memophenol™), can impact gut health and brain function amid chronic inflammation.
- The research found that Memophenol™ can reduce harmful gut-derived compounds (indoxyl sulfate and trimethylamine N-oxide) linked to inflammation, and it alters the gut microbiome composition in mice.
- Furthermore, Memophenol™ intake helped maintain the integrity of brain blood vessel junctions and reduced markers related to neurodegeneration, suggesting its potential protective effects on both gut microbiota and brain health.
Article Synopsis
- The study focuses on improving early detection and treatment of osteosarcoma (OS) by examining circulating miRNAs as a non-invasive diagnostic tool.
- Utilizing RNAseq and PCR Array data, researchers identified 43 significantly expressed miRNAs and developed a diagnostic model based on four specific miRNAs, showing high accuracy in distinguishing OS patients from healthy individuals.
- The research reveals that the down-regulation of these miRNAs is linked to poor prognosis and lower survival rates, indicating their potential role as tumor suppressors and establishing connections to key cancer-related signaling pathways, paving the way for future therapeutic strategies.