A novel fluoro colorimetric Loop mediated isothermal amplification (LAMP) assay for detection of Trichomonasvaginalis.

Background: Trichomoniasis is a curable, non-viral, sexually transmitted infection. Early diagnosis and treatment of cases can prevent complications and further spread of infection. Rapid diagnostics tests, which can be performed on-site, will help in early diagnosis.

In Vitro Efficacy of Biocompatible Zinc Ion Chelating Molecules as Metallo-β-Lactamase Inhibitor among NDM Producing .

 This article assesses the effectiveness of captopril, tetracycline, and ciprofloxacin as metallo-β-lactamase (MBL) inhibitors against New Delhi metallo-β-lactamase (NDM)-producing  Twenty-four well-characterized carbapenem-resistant isolates which produced NDM (  = 21) and Oxa-48-like enzymes (  = 3) were used to assess the inhibitors. The positive control organism was designed by cloning the NDM gene into pET-24a plasmid and transforming it into expression vector BL21. All the proposed inhibitors were assessed for their interaction with MBLs using checkerboard minimum inhibitory concentration (MIC) assay with imipenem and meropenem.

Pneumoperitoneum from pneumomediastinum in paraquat poisoning.

Pneumomediastinum is not uncommon in paraquat poisoning and usually results from oesophageal perforation or alveolar rupture in fibrotic lung disease. However, the combined presentation of pneumomediastinum and pneumoperitoneum is a rarity. We recently managed a young patient with paraquat ingestion who developed spontaneous pneumomediastinum.

Axial super-resolution in ultrasound imaging with application to non-destructive evaluation.

A fundamental challenge in non-destructive evaluation using ultrasound is to accurately estimate the thicknesses of different layers or cracks present in the object under examination, which implicitly corresponds to accurately localizing the point-sources of the reflections from the measured signal. Conventional signal processing techniques cannot overcome the axial-resolution limit of the ultrasound imaging system determined by the wavelength of the transmitted pulse. In this paper, starting from the solution to the 1-D wave equation, we show that the ultrasound reflections could be effectively modeled as finite-rate-of-innovation (FRI) signals.