Publications by authors named "S M Reid"

Objectives: To calculate a polygenic risk score (PRS) based on single nucleotide variants (SNVs) previously associated with primary Sjögren's disease (SjD) with genome-wide significance, and determine the genetic risk for SjD stratified by antibodies, sex and age at diagnosis.

Methods: Patients with SjD (n = 1065) were genotyped using Illumina OmniExpressExome chip. Control genotype data were available (n = 7742).

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Article Synopsis
  • Pediatric pneumonia diagnoses are tricky due to overlapping symptoms with other respiratory issues, subjective radiograph interpretations, and non-diagnostic lab results.
  • The study analyzed children aged 3 months to 16 years in Canadian EDs before COVID-19, focusing on how accurately physicians could classify pneumonia types using an expert panel for consensus diagnosis.
  • Findings showed a significant mismatch between physicians’ diagnoses and consensus results, with over-diagnosis of typical bacterial pneumonia and recommendations for specific clinical and lab indicators to better identify bacterial cases.
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Article Synopsis
  • The study examines factors influencing the completion of alcohol and other drug (AOD) treatment, focusing on both demographic and service-level aspects among a large cohort in New South Wales, Australia.
  • It found that around 69.8% of participants completed treatment at least once, with differences in completion rates based on the type of substance, treatment modality, and referral source.
  • Specifically, amphetamine treatments had the lowest completion rates, while mandated treatments through criminal justice agencies and certain AOD modalities, like involuntary treatments, showed significantly higher completion rates.
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