Publications by authors named "S M Nasereddin"
Article Synopsis
- * Utilizing data from 26 studies published between 1990 and 2019, the results revealed that about 55% of suspected onychomycosis cases were confirmed through PCR analysis, with dermatophytes being the most common infective organisms; specific groups like females and residents of arid countries showed unique trends.
- * It was found that 90% of countries assessed lacked access to the most effective topical treatments, with Africa facing the greatest access challenges, highlighting a significant global issue in the availability of effective therapies for fungal infections. *
Recalcitrant nail plate infections can be life-long problems because localizing antifungal agents into infected tissues is problematic. In this systematic review, guided by the SPIDER method, we extracted chemical nail permeation data for 38 compounds from 16 articles, and analyzed the data using quantitative structure-property relationships (QSPRs). Our analysis demonstrated that low-molecular weight was essential for effective nail penetration, with <120 g/mol being preferred.
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