The clinical forms of systemic neuroendocrine pathology (neuroendocrine cybernosis).

Six forms of regulation of neuroendocrine system pathology are here presented. For this pathogenic category it was proposed the term of "systemic neuroendocrine pathology" (1979) and that of "endocrine cybernosis (1971) for its clinical forms. Clinical and pathogenic peculiarities of endocrine blocking cybernoses with negative feed-back disappearance, substitution cybernose as in Graves-Basedow's syndrome and hormonal circadian rhythm troubles are described.

Blocking cybernosis in endocrine glands pathology.

The term cybernosis was proposed by Meerloo (1971) in order to designate the cybernetic functional disorders in senescence. Blocking cybernosis or bloking negative feedback is the term used for negative feedback perturbation in a neuro-endocrine subsystem caused by factors dwelling inside or outside it. Using the hypothalamo-hypophyso-adrenocortical subsystem as a model, the author shows that due to an excessive and anarchic secretion of corticoids by a tumor developed in the adrenocortical, the hypothalamo-hypophyseal control centers are blocked.