Publications by authors named "S M Mayeur"
Article Synopsis
- A case study is presented of a patient whose postchemotherapy thymic teratoma developed an MNT component and later experienced vertebral metastasis corresponding to anaplastic MNT, highlighting the complications that can arise from teratomas.
- Genetic analysis revealed 19 shared somatic mutations among the tumor components, with several mutations found in known cancer-related genes, suggesting a potential pathway for the progression of MNT transformation and underscoring the need for
Objective: To study whether the occurrence and type of placental lesions vary according to the time of onset of COVID-19 in pregnant women.
Design: Case-control study.
Setting: Departments of Gynaecology-Obstetrics and Pathology, Strasbourg University Hospital, France.
Background: The dystonias are a heterogeneous group of hyperkinetic disorders characterized by sustained or intermittent muscle contractions that cause abnormal movements and/or postures. Although more than 200 causal genes are known, many cases of primary dystonia have no clear genetic cause.
Objectives: To identify the causal gene in a consanguineous family with three siblings affected by a complex persistent generalized dystonia, generalized epilepsy, and mild intellectual disability.
Article Synopsis
- The study explores the unknown factors driving severe COVID-19 by examining a young patient cohort without major comorbidities, comparing critical and non-critical cases.
- Researchers used advanced techniques like whole-genome sequencing and artificial intelligence to analyze biological samples and found significant inflammatory responses and immune system alterations in critical patients.
- A specific gene signature was identified that distinguished critical cases and indicated that inhibiting the ADAM9 gene could reduce SARS-CoV-2 infection and replication, suggesting potential therapeutic options.