Impacts of microplastics on ecosystem services and their microbial degradation: a systematic review of the recent state of the art and future prospects.

Microplastics are tiny plastic particles with a usual diameter ranging from ~ 1 μ to 5 µm. Recently, microplastic pollution has raised the attention of the worldwide environmental and human concerns. In human beings, digestive system illness, respiratory system disorders, sleep disturbances, obesity, diabetes, and even cancer have been reported after microplastic exposure either through food, air, or skin.

Groundwater geochemistry using modified integrated water quality index (IWQI) and health indices with special emphasis on nitrates and heavy metals in southern parts of Tirupati, South India.

Groundwater is particularly vulnerable to pollution in places with a high population density and extensive human usage of the land, especially in southern parts of Tirupati, India. To assess this, 60 bore-well samples were obtained and assessed for physical specifications, ion chemistry, and heavy metals during the pre- and post-monsoon seasons 2022. The current investigation employed a modified integrated water quality index (IWQI), conventional graphical and human health risk assessment (HHRA) of nitrates and heavy metals to know the groundwater chemistry and its detrimental health effects on humans.

Comparative Study of the Influence of Dental Implant Design on the Stress and Strain Distribution using the Finite Element Method.

Background: One emerging and important research method for biomechanical assessments in biological investigations is the finite element analysis (FEA). It is the best technique for simulating intricate structures and examining their mechanical characteristics.

Aim: This study was conducted to compare the V-shaped design and square thread design regarding their influence on the stress and strain distribution using the finite element method.

Frameshift Mutations in Leukemia-Associated Genes Correlate With Superior Outcomes in Patients Undergoing Allogeneic Stem Cell Transplant for Acute Myeloid Leukemia.

Background: Allogeneic stem cell transplant (allo-SCT) is a mainstay of treatment for acute myeloid leukemia (AML). Its success depends largely on response of donor T lymphocytes against leukemia cells, known as graft-vs-leukemia (GvL) effect. A key potential driver of GvL is immune response to mutation-derived neoantigens.

Biopolymeric nanoencapsulation of model drug: Its development and characterisation.

This research aimed to develop the phenytoin-loaded bionanosuspension by utilising the novel biopolymer from Juglans regia andreduce the long-term treatment cost of epilepsy and increase the efficiency of therapy. A novel biopolymer with remarkable inbuilt properties was isolated and used in the development of a nano capsulated dispersed system. The diverse proportions of phenytoin and biopolymer with different ratios 1:2, 1:3, 1:4, 1:5 and 1:8 were taken for the planning of details PJNC1-PJNC5.