Publications by authors named "S M MacLeod"

Article Synopsis
  • Street and working children (SWC) face numerous challenges, including violence and limited access to healthcare, highlighting the need for better understanding of their rights in this area.
  • The study conducted extensive research from 2000 to present, identifying 35 relevant studies that primarily focused on aspects like trafficking and exploitation, mostly in Africa and the USA.
  • Findings show that barriers such as cost, stigma, and legal issues hinder healthcare access for SWC, while support and proactive healthcare use can facilitate access; there is an urgent need for improved training for healthcare professionals to address these issues.
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Objective: POLR3B encodes the second largest subunit of RNA polymerase III, which is essential for transcription of small non-coding RNAs. Biallelic pathogenic variants in POLR3B are associated with an inherited hypomyelinating leukodystrophy. Recently, de novo heterozygous variants in POLR3B were reported in six individuals with ataxia, spasticity, and demyelinating peripheral neuropathy.

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Aim: With an ageing population the prevalence of dementia increases. A healthcare crisis is looming.

Method: Dementia is a terminal condition.

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Article Synopsis
  • Viruses pose significant threats to global health and economies, necessitating a deeper understanding of their infectious states.
  • Current methods for studying viruses are largely inadequate, prompting the need for better techniques.
  • The new FAIRY assay can quickly distinguish between intact and nonintact enveloped viruses, showcasing its potential for studying viral infectivity and treatment applications.
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The population of people in federal custody in Canada is aging. Those in custody report experiencing poorer health and high rates of chronic health conditions. Two health concerns that are disproportionately higher among those in custody are mood disorders and pain.

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