Efficient matrix-assisted refolding of the recombinant anti-staphylococcal truncated endolysin LysKCA and its structural and enzymatic description.

The recombinant truncated endolysin LysK consisting of two catalytic domains, N-terminal CHAP and amidase-2 (LysK) was overexpressed in E. coli in the form of inclusion bodies (IBs). These IBs were dissolved in 6 M solution of urea followed by the refolding process.

Optimizing Motion-Planning Problem Setup via Bounded Evaluation with Application to Following Surgical Trajectories.

A motion-planning problem's setup can drastically affect the quality of solutions returned by the planner. In this work we consider optimizing these setups, with a focus on doing so in a computationally-efficient fashion. Our approach interleaves optimization with motion planning, which allows us to consider the actual motions required of the robot.

Pituitary macroadenoma presenting as severe hyponatremia: a case report.

Background: Hyponatremia is defined as a serum sodium level of less than 135 mEq/L in a patient. Although hyponatremia is not an uncommon laboratory finding, especially in the elderly, hunting for the etiology is a challenging issue for any clinician. The three first-line investigations that are required for further analysis are urine osmolality, serum osmolality, and urinary sodium levels in addition to clinical assessment of volume status.