[Morphological changes in the ocular structures in the simulation of proliferative vitreoretinopathy and in the presence of an extraocular focus of chronic infection].

The pathomorphological features of proliferative vitreoretinopathy (PVR) were studied in the presence or absence of an extraocular focus of chronic infection. The study was performed on 60 Chinchilla rabbits. In experimental animal group 1, the left eyes were used to simulate a thrombocytic model of PVR; physiological sodium chloride solution was injected into the right eyes that served as control.

[Ultrastructure of optic nerve fibers in rabbits after intravitreal infusion of perfluoroorganic compounds].

Ultrastructure of optic nerve myelinated fibers after intravitreal infusion of perfluorooctylbromide (PFOB) and perfluorodecaline (PFD) for 30 days was studied in rabbits (n = 14). After inraocular administration of PFOB, the ultrastructural changes of optic nerve fibers were mainly reactive in nature. Mitochondrial swelling and partial destruction of cristae were detected in the axons.