Publications by authors named "S M Ksenzenko"

Article Synopsis
  • Chronic sun exposure leads to common skin issues like wrinkles and pre-cancerous growths, particularly affecting the driver's side of the face due to UVA rays from sunlight while driving.
  • A study evaluated the effectiveness of auto glass and UV-blocking window film in reducing UV damage through a photoprotection assay.
  • Results showed that while auto glass reduced cell damage by 29%, UV film alone decreased it by 90%, and the combination of both offered a 93% reduction, highlighting the film's potential to significantly protect against UV-related skin damage and conditions.
View Article and Find Full Text PDF

Background: Many light- and laser-based systems are used to reduce cutaneous wrinkles, and some have been shown to stimulate dermal collagen production. Using the ThermaCool TC radiofrequency device to treat bovine tendon and human abdominal skin, we documented the cutaneous effects of a radiofrequency-based system for nonablative treatment.

Observations: Electron microscopy of bovine tendon treated at varied heat and cooling settings revealed collagen fibrils with increased diameter and loss of distinct borders as deep as 6 mm.

View Article and Find Full Text PDF

Background: Ultraviolet (UV) radiation damages skin through a variety of mechanisms, including the generation of free radicals. Gluconolactone is a polyhydroxy acid (PHA) that is capable of chelating metals and may also function by scavenging free radicals, thereby protecting skin from some of the damaging effects of UV radiation.

Objective: This study measured the ability of gluconolactone to protect against UV radiation-induced damage.

View Article and Find Full Text PDF

Surfactant functional effectiveness is dependent on phospholipid compositional integrity; sepsis decreases this through an undefined mechanism. Sepsis-induced hypothyroidism is commensurate and may be related. This study examines the effect of 3,3',5-triiodo-L-thyronine (T3) supplementation on surfactant composition and function during sepsis.

View Article and Find Full Text PDF

Background: Long surfactant phospholipids are altered during sepsis; the role of surfactant apoproteins is unknown. This study investigates the effect of cecal ligation and puncture (CLP) on surfactant functional effectiveness and apoprotein transcriptional activity with or without T3 replacement.

Methods: Male Sprague Dawley rats underwent sham laparotomy or CLP with or without T3 replacement.

View Article and Find Full Text PDF