Maintaining stringent conditions in SELEX (Systematic Evolution of Ligands by EXponential enrichment) is crucial for obtaining high-affinity aptamers. However, excessive stringency greatly increases the risk of SELEX failure. Controlling stringency has remained a technical challenge, largely dependent on intuition, due to the absence of a clear, quantitative measure of stringency.
View Article and Find Full Text PDFTwo-dimensional materials with new physical phenomena are gaining popularity due to their unique properties. In recent years, a new family of layered compounds inspired by the minerals valleriite and tochilinite which are composed of alternating quasi-atomic sheets of transition metal chalcogenides (sulfides and selenides of Fe, Fe-Cu and other metals) and hydroxides of Mg, Al, Fe, Li, ., assembled electrostatic interaction, has arisen as a new synthetic platform for 2D materials.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
December 2024
The study of Na-carbonates stability and their transformations in aqueous carbonate fluid under high P-T conditions is relevant from the point of view of the understanding geochemical processes of the Na-assisted carbon circulation in the Earth's crust and subduction zones. In situ Raman study of Na-bearing carbonate-water-Fe-metal system in diamond anvil cell (DAC) at high P-T conditions revealed that carbonates decompose with abiogenic formation of formates and other organic compounds that differs from behavior of carbonates in dry system. XRD and FTIR methods have been used additionally to determine the phase composition.
View Article and Find Full Text PDFProbl Sotsialnoi Gig Zdravookhranenniiai Istor Med
May 2024
The article considers evaluation of works of colleagues and contemporaries of N. P. Kravkov, the creator of "Russian narcosis" with hedonal.
View Article and Find Full Text PDFProbl Sotsialnoi Gig Zdravookhranenniiai Istor Med
March 2024
The article analyses research activities of the discoverers of "Russian narcosis" from the Military Medical Academy of St. Petersburg: the head of the Department of Pharmacology N. P.
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