Lipid peroxidation and antioxidant status in hypertensive pregnancies.

Aims And Objective: The present study was designed to evaluate the lipid peroxidation and non-enzymatic antioxidant status in hypertensive complications during pregnancy (preeclamptic and eclamptic) compared with healthy pregnant and non-pregnant patients as controls.

Materials And Methods: 25 healthy non-pregnant women as controls, 25 third trimester normal pregnant women and 25 preeclamptic and 25 eclamptic patients of the same trimester. Lipid peroxidation as a thiobarbituric acid reactive substance reduced glutathione, Vitamin E, Vitamin C and Vitamin A.

Role of lipid peroxidation and enzymatic antioxidants in pregnancy-induced hypertension.

Aims And Objectives: Preeclampsia remains a major cause of maternal mortality and morbidity. It is a leading indication for iatrogenic premature delivery. Oxidative stress is considered to be one of the factors in the disease process.

Correlation between lipid peroxidation and non-enzymatic antioxidants in pregnancy induced hypertension.

The present study was designed to evaluate the lipid peroxidation and non-enzymatic antioxidants in pregnancyinduced hypertension (PIH) compared with healthy normal pregnant and non-pregnant as controls. 75 cases were studied of which 25 were normal healthy controls (Group A), 25 healthy pregnant women (Group B) of third trimester and 25 were PIH (Group C) of the same trimester. In PIH, malondialdehyde a lipid peroxidation product was significantly increased as compared to normal pregnant and non-pregnant controls.

Study of oxidative stress and enzymatic antioxidants in normal pregnancy.

Pregnancy is a physiological state accompanied by a high-energy demand and an increased oxygen requirement. Augmented levels of oxidative stress would be expected because of the increased intake and utilization of oxygen. Evidence of increased oxidative stress in normal pregnancy in comparison with nonpregnant controls was estimated by measuring Thiobarbituric acid reactive substance (TBARS), enzymatic antioxidants like Superoxide dismutase, Glutathione peroxidase, Glutathione reductase and catalase.