Publications by authors named "S M Kawale"

Article Synopsis
  • - A new micro-reaction process has been developed to easily synthesize ionizable and cationic lipids for nanoparticle carriers, avoiding the complications and dangers of traditional batch methods.
  • - The process efficiently converts moisture-sensitive acyl chlorides and includes steps to remove toxic byproducts, allowing for the production of about 10 grams of lipids per hour.
  • - The synthesized lipids can be transformed into uniform-sized lipid nanoparticles and liposomes, enhancing the potential for practical use in lipid-based nanomedicines.
View Article and Find Full Text PDF

Since there is a clear correlation between poverty and corruption, mathematicians have been actively researching the concept of poverty and corruption in order to develop the optimal strategy of corruption control. This work aims to develop a mathematical model for the dynamics of poverty and corruption. First, we study and analyze the indicators of corruption and poverty rates by applying the linear model along with the Eviews program during the study period.

View Article and Find Full Text PDF

The diastereoselective formal synthesis of (-)-quinagolide, a D receptor agonist, has been achieved. The synthesis started from l-pyroglutamic acid and relied on utilization of (a) a stereospecific catalytic hydrogenation and diastereoselective Horner-Emmons-Michael cascade to obtain functionalized prolinate, (b) a Lewis acid mediated Pummerer cyclization to construct a tricyclic fused ring system, and (c) a diastereoselective ring expansion via a bicyclic aziridinium intermediate to access the required 3-substituted piperidine scaffold.

View Article and Find Full Text PDF

Fractional-order derivative-based modeling is very significant to describe real-world problems with forecasting and analyze the realistic situation of the proposed model. The aim of this work is to predict future trends in the behavior of the COVID-19 epidemic of confirmed cases and deaths in India for October 2020, using the expert modeler model and statistical analysis programs (SPSS version 23 & Eviews version 9). We also generalize a mathematical model based on a fractal fractional operator to investigate the existing outbreak of this disease.

View Article and Find Full Text PDF

Hand, foot and mouth disease (HFMD) is a paediatric disease associated with enteroviruses (EVs). Among EVs, coxsackievirus A-16 (CVA-16) strain is currently in circulation and causing outbreaks in India. Neonatal mice (Institute of Cancer Research) strains were infected with CVA-16 strain isolated from HFMD patients to conduct pathological and molecular studies.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessiongf7ee2selm3p6rimsams58eoo6nhrrnp): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once