Diagnostic performance of the hologic genius digital diagnostics system for low-grade squamous intraepithelial lesion (LSIL) ThinPrep papanicolaou tests.

Introduction: Advancements in digital imaging technology for Papanicolaou test slides, combined with artificial intelligence are driving the development and adoption of innovative computer-assisted screening methods for cervical cancer within the cytology community. Our study aimed to assess the performance of the Hologic Genius Digital Diagnostic System (HGDDS) in the interpretation of low-grade squamous intraepithelial lesions (LSIL) in ThinPrep Papanicolaou slides.

Method: As part of a validation study performed with 890 ThinPrep Papanicolaou slides using the HGDDS, a subset of 146 LSIL cases were included in this study.

Impact of Tumor Stage on Oncologic Outcomes of High-grade Bacillus Calmette-Guérin Unresponsive Non-muscle-invasive Bladder Cancer Undergoing Bladder-sparing Therapies.

Background And Objective: Current data on bacillus Calmette-Guérin (BCG)-unresponsive non-muscle-invasive bladder cancer (NMIBC) do not differentiate outcomes by clinical stage. The purpose of this study is to investigate the role of tumor stage in oncologic outcomes in BCG-unresponsive NMIBC undergoing bladder-sparing therapies.

Methods: Demographic and outcome data for patients with BCG-unresponsive NMIBC were reviewed at ten institutions.

Establishment of a Research Unit in Colac, a Medium Rural Town: An Update on Progress and Guidance for Rural Health Service Research Strategy Development.

Background: Rural health services have not had the same opporunities for research as metropolitan health services. Despite increasing awareness of the importance of placed-based research led by rural health services, there are few examples in the literature on how this can be done.

Aims: In this AJRH Practice Insight we aim to provide an update on the establishment and progress of the Colac Area Health (CAH) research unit.

The parenthood journey in radiology: Challenges and opportunities.

The journey to parenthood is often delayed or prolonged for physicians, which disproportionately negatively impact women physicians. Women radiologists may delay childbearing for many reasons, which may lead to higher rates of regret and greater risks of infertility and pregnancy and postpartum complications. A better understanding of the resources and realities to achieve parenthood allows for more timely family planning while pursuing career advancements in radiology, particularly for medical students and our radiology trainees and early-career colleagues.

Thermalization and criticality on an analogue-digital quantum simulator.

Understanding how interacting particles approach thermal equilibrium is a major challenge of quantum simulators. Unlocking the full potential of such systems towards this goal requires flexible initial state preparation, precise time evolution and extensive probes for final state characterization. Here we present a quantum simulator comprising 69 superconducting qubits that supports both universal quantum gates and high-fidelity analogue evolution, with performance beyond the reach of classical simulation in cross-entropy benchmarking experiments.