Publications by authors named "S M German"

Article Synopsis
  • Cytomegalovirus (CMV) is the most common viral infection in kidney transplant recipients (KTRs) and can range from asymptomatic cases to serious organ-specific issues, making it particularly important post-transplant.
  • This study focused on identifying the frequency of CMV-associated colitis in KTRs experiencing lower gastrointestinal bleeding, enrolling 95 participants within a year-long timeframe.
  • Results revealed that 22.1% of those studied had CMV colitis, with most patients (76.8%) presenting with fresh rectal bleeding, alongside findings of colonic ulcers and erosions in a significant portion of the cohort.
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Article Synopsis
  • - A brain abscess is a localized area of dead tissue in the brain caused by infection (or sometimes trauma), characterized by a membrane surrounding the necrosis.
  • - The case described involves a young, otherwise healthy female with multiple brain abscesses in her left and right brain regions, presenting unusual symptoms like weakness in both legs, seizures, and fever.
  • - After receiving treatment that included draining the abscess and antifungal medications, the patient's acute kidney injury improved, leading to recovery as shown in both her clinical status and medical imaging.
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Modification of T-lymphocytes, which are capable of paracellular transmigration is a promising trend in modern personalized medicine. However, the delivery of required concentrations of functionalized T-cells to the target tissues remains a problem. We describe a novel method to functionalize T-cells with magnetic nanocapsules and target them with electromagnetic tweezers.

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Simultaneous multipass resistive-pulse sensing and fluorescence imaging have been used to correlate the size and fluorescence intensity of individual lipid liposomes composed of polar lipid extracts labeled with membrane-bound 3,3-dioctadecyloxacarbocyanine (DiO) fluorescent molecules. Here, a nanopipet serves as a waveguide to direct excitation light to the resistive-pulse sensing zone at the end of the nanopipet tip. Individual DiO-labeled liposomes (>50 nm radius) were multipassed back and forth through the orifices of glass nanopipets' 110-150 nm radius via potential switching to obtain subnanometer sizing precision, while recording the fluorescence intensity of the membrane-bound DiO molecules.

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