Water pollution from the industrial dyes is a serious hazard to ecosystems, and addressing this issue is a significant challenge. To address these issues, we are fabricated BaDyFeO (x = 0.02 to 0.
View Article and Find Full Text PDFTopical steroid withdrawal (TSW) is a controversial diagnosis advocated by patients but often confused for atopic dermatitis. We conducted a multimodal pilot study of 16 patients fitting the TSW diagnostic profile, contrasting them against patients with atopic dermatitis (n = 10) and healthy controls (n = 11). Our clinical evaluations established objective diagnostic criteria that distinguish TSW from atopic dermatitis, metabolomics and transcriptomics of skin biopsies suggested that neuroinflammatory pathways are associated with complex I-mediated oxidation of NAD+, cellular and mouse models demonstrated that NAD+ metabolism was proinflammatory and glucocorticoid responsive, whereas functional assays demonstrated that the metabolic effects of glucocorticoids on the only cell type that aligns with the distribution and duration of TSW pathology could be mitigated by complex I blockade.
View Article and Find Full Text PDFIndividuals with cancer exposed to SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), are more susceptible to COVID-19-related complications [...
View Article and Find Full Text PDFBackground: The present investigation is motivated by the fact that the incidence of visual impairment is increasing all over the world. Visually challenged people may encounter specific problems in maintaining their oral hygiene, leading to a higher risk of periodontal diseases.
Materials And Methods: This comparative study was conducted among visually challenged 5-20 year old school children.
Ovarian cancer (OC) is an aggressive malignancy of the female reproductive organs, associated with a low 5-year survival rate. Emerging evidence suggests the pivotal role of microRNAs (miRNAs) in regulating chemoresistance and metastasis in OC, primarily through cancer stem cells (CSCs), also known as cancer stem-like cells (CSLCs). Herein, we demonstrate that miR-379-5p is downregulated in several OC cell populations including both cell lines and patient tumor samples.
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