Publications by authors named "S M Furgal"

The results of the study of the parameters of the immune system in persons suffering from frequent infections, bacteriocarriers and persons with nonspecific infections are presented. The study revealed that T-cell deficiency of the 2nd and 3rd degrees could be regarded as the universal marker of decreased immune reactiveness. Sodium nucleinate was found to be capable of stimulating the T-cell element of immunity and antibody formation, which made it possible to achieve a considerable decrease in morbidity rate.

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On the basis of complex analysis of the present situation and problems of immunization in the Armed Forces the authors worked out the scientific substantiation of the principles and trends towards the improvement of immunoprophylaxis among servicemen. The article provides epidemiological evidence concerning the necessity to make a transition to a principle of a complex associated immunization, maintaining unchanged three basic regional schemes, as well as a 2-stage immunization with different approach to the various categories of servicemen, and a 4-5-valent protective vaccine complex for the first-term enlistees. The authors worked out a variant of a calendar and schedules for prophylactic vaccination of personnel in the Armed Forces of Russian Federation in peaceful time.

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The article analyses the results of controlled epidemiologic observation made in military unit to estimate the immunological and clinico-epidemiological efficiency of national inactivated influenza vaccines with different valency and antigen charge in inoculative dose. The analysis proves the high immunogenic activity and protective features of inactivated influenza trivaccines with enhanced contents of hemagglutinins. The article substantiates the reasons for mass application of these vaccines in military units with obligatory addition of B-component and enhanced antigen contents of vaccine viruses in inoculative dose.

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