Chronic stress modulates the expression level of leptin and leptin receptors in the hypothalamus of male rats with a history of maternal stress.

The activity of different neurotransmitter pathways in the hypothalamus controls the stress response. Meanwhile, leptin is known as an effective mediator in the stress response, and its serum and brain levels change when exposed to stressful factors. In this study, the effect of chronic social instability stress (INS) and chronic unpredictable stress (CUS) on anxiety-like behavioral responses and the level of expression of leptin and its receptor in the brain of male Wistar rats that were under maternal stress (MS) were investigated.

Biofunctionalized CdS Quantum Dots: A Case Study on Nanomaterial Toxicity in the Photocatalytic Wastewater Treatment Process.

The toxic nature of inorganic nanostructured materials as photocatalysts is often not accounted for in traditional wastewater treatment reactions. Particularly, some inorganic nanomaterials employed as photocatalysts may release secondary pollutants in the form of ionic species that leach out due to photocorrosion. In this context, this work is a proof-of-concept study for exploring the environmental toxicity effect of extremely small-sized nanoparticles (<10 nm) like quantum dots (QDs) that are employed as photocatalysts, and in this study, cadmium sulfide (CdS) QDs are chosen.

Improvement in use of best practice in the care of patients with oral mucositis in a comprehensive cancer center in Iran: a best practice implementation case study.

Introduction: Oral mucositis is a common debilitating complication of cancer treatments, particularly chemotherapy and radiation.

Objectives: The purpose of this study was to improve oral mucositis prevention and control among cancer patients through the implementation of best practice guidelines in a tertiary referral center in Northern Iran.

Methods: A clinical audit design was utilized in this implementation project.

Identification of core micropollutants of Ergene River and their categorization based on spatiotemporal distribution.

Ergene River is heavily utilized for irrigation of fields to grow the main stocks of rice, wheat, and sunflower of Turkey also exported to Europe; therefore, monitoring the river's water quality is crucial for public health. Although the river quality is routinely monitored, the evaluation of pollution based on micropollutants is limited. In this study, we measured 222 organic micropollutants in 300 samples collected from 75 different locations on the Ergene River between August 2017 and May 2018 using direct injection liquid chromatography-tandem spectrometry with optimized scheduled multiple reaction monitoring.