[Regulation of content of cytokines in blood serum and of caspase-3 activity in brains of old rats in model of sharp hypoxic hypoxia with Cortexin and Pinealon].

While studying the effects of Cortexin and Pinealon (Glu-Asp-Arg) on the caspase-3 activity in the brain, an interleykin-6 and a factor of tumor necrosis in blood serum of old rats under the sharp hypoxic hypoxia it was suggested that in hypoxia of brain conditions Pinealon forwards the increase of the neurogenesis and the decrease neuroinflammatory reactions to a reference level. With the sharp hypoxic hypoxia Cortexin reduces an ability of brain tissue of programmed cells death, but saves the content of interleykin-6 at high level.

[Fisiological aspects of host--microorganisms interreaction: the role of neurotransmitter amines].

Ability to use catecholamines as a stimulus for growth and pathogenic activity realization is widespread among bacteria. In the review numerous facts testifying the ability of these substances to stimulate pathogenic microflora development are systematized and mechanisms of growth stimulation and change of genes expression of microorganisms by catecholamines are considered. The microbial endocrinology role in shaping integrative physiological concepts is discussed.

[Effect of serotonin and dopamine on growth of Yersinia pestis and Francisella tularensis strains].

Aim: To study the effects of serotonin and dophamine on the growth of Yersinia pestis and Francisella tularensis strains as well as ability of monoamines to change susceptibility of experimental animals to plague infection.

Materials And Methods: Effect of various doses of biogenic amines on the growth of Y. pestis and F.