Publications by authors named "S M Cruise"
Article Synopsis
- Supraventricular tachycardia (SVT) is a common heart rhythm issue in children, with vagal maneuvers being effective less than 50% of the time, so adenosine is used as the first-line treatment despite minor side effects.
- A study reviewed the use of adenosine in kids under 18 at two emergency departments over a span of 20 years to understand the incidence of serious side effects.
- The results showed that while 17 patients had brief ventricular beats post-administration, no serious complications like syncope occurred, and one patient experienced temporary hypotension that resolved on its own.
In preclinical traumatic brain injury (TBI) research, the animal model should be selected based on the research question and outcome measures of interest. Direct side-by-side comparisons of different injury models are essential for informing such decisions. Here, we used immunohistochemistry to compare the outcomes from two common models of TBI, lateral fluid percussion (LFP) and repeated mild weight drop (rmWD) in adult female and male Wistar rats.
View Article and Find Full Text PDFBackground: Aimed to compare the prevalence, characteristics, and associated mortality risk of frailty in Northern Ireland (NI) and the Republic of Ireland (ROI).
Methods: Secondary analysis of the first wave of two nationally representative cohorts, the Northern Ireland Cohort for the Longitudinal Study of Ageing or NICOLA study (N = 8504) and the Irish Longitudinal Study on Ageing or TILDA study (N = 8504). Frailty was assessed using a harmonized accumulation deficits frailty index (FI) containing 30 items.
Traumatic brain injury (TBI) heterogeneity has led to the development of several preclinical models, each modeling a distinct subset of outcomes. Selection of an injury model should be guided by the research question and the specific outcome measures of interest. Consequently, there is a need for conducting direct comparisons of different TBI models.
View Article and Find Full Text PDFTraumatic brain injury (TBI) and alcohol misuse are inextricably linked and can increase the risk for development of neurodegenerative diseases, particularly in military veterans and contact sport athletes. Proteinopathy (defects in protein degradation) is considered an underlying factor in neurodegenerative diseases. Whether it contributes to TBI/alcohol-mediated neurodegeneration is unexplored, however.
View Article and Find Full Text PDF