Development of computational information technology for monitoring NCD risks in the Russian population: preliminary results.

Here, we report first results on the development of computational health information technology for monitoring chronic non-communicable diseases (NCDs) risks in Russia based on data of the large-scale ongoing population survey in Health Centers (HCs). The technology involve algorithms for automated raw data process and generation of joint database, tools for data standardization and visualization, the assessment of risks, and other components. The data on physical status of Russians, including height, weight, and BMI are provided and compared with Belgian (1835), Swiss (2002), and US (1988-1994) reference datasets.

[Obtaining and characteristics of domestic preparation interferon alpha-2b with prolonged effect].

Pegylated interferon alpha-2b (PEG-IFN alpha-2b) is a domestic preparation of a modified recombinant interferon alpha-2b with prolonged effect. The preparation was obtained by N-terminal pegylation of IFN alpha-2b with polyethylene glycol (PEG). This paper presents the method of PEG-IFN alpha-2b synthesis and characteristics of the obtained product.

[New ways to increasing the yield of laccase from Panus tigrinus fungi].

We optimized the conditions for production of laccase by lignolytic fungi Panus tigrinus 8/18. 2,4-Dimethylphenol was used as an aromatic inductor. The addition of 2,4-dimethylphenol and 2 mM CuSO4 to a rich medium was followed by a tenfold increase in the yield of this enzyme.

[Hormonal correction of the resident microflora of the vagina and uterus cervix in women with chronic cervicitis].

Clinical, microbiological and hormonal examination of women with chronic cervicitis revealed lesions in the upper section of the reproductive tract in a high proportion of those examined, hormonal disturbances being registered in 96.7% of women. Dysbiotic manifestations (suppression of lacto- and bifidoflora and the excessive growth of opportunistic microorganisms) in the uterus cervix and vagina observed in patients with chronic cervititis were not associated with the etiology of the inflammatory process.