Publications by authors named "S M Cash"

The consumption of sugar-sweetened beverages (SSBs) is associated with type 2 diabetes (T2D) and cardiovascular diseases (CVD). However, an updated and comprehensive assessment of the global burden attributable to SSBs remains scarce. Here we estimated SSB-attributable T2D and CVD burdens across 184 countries in 1990 and 2020 globally, regionally and nationally, incorporating data from the Global Dietary Database, jointly stratified by age, sex, educational attainment and urbanicity.

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Objective: Although seizures are the cardinal feature, epilepsy is associated with other forms of brain dysfunction including impaired cognition, abnormal sleep, and increased risk of developing dementia. We hypothesized that, given the widespread neurologic dysfunction caused by epilepsy, accelerated brain aging would be seen. We measured the sleep-based brain age index (BAI) in a diverse group of patients with epilepsy.

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  • * Thalamo-cortical spindles and Up states are crucial in coordinating co-ripples in the cortex and hippocampus during non-REM sleep.
  • * The study suggests that instead of direct thalamic ripples, spindles and Up states are key in integrating information for memory consolidation during sleep.
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  • Anxiety and depressive disorders can lead to cognitive control deficits, but the specific brain mechanisms behind this are still unclear.
  • Researchers studied participants with refractory epilepsy to see how anxiety/depression affected their brain and behavior during a cognitive task, using high-resolution EEG.
  • Key findings revealed that those with anxiety/depression took longer to respond under cognitive load but maintained response accuracy, with notable changes in brain activity patterns in regions linked to conflict processing, suggesting increased cognitive resource demands due to inefficient processing.
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  • Cognitive motor dissociation (CMD) involves patients who can follow commands in brain scans like fMRI, despite showing no behavioral signs of language function, highlighting the importance of accurate diagnosis in severe brain injuries.
  • Recent findings outline a structured approach for assessing CMD at clinical institutions, underlining the need for ethical considerations, standardized protocols, and effective communication of results.
  • The proposed method for CMD assessment aims to be adaptable, allowing for updates and improvements as more evidence becomes available in the field.
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