Publications by authors named "S Lyon"

Background:  High levels of precision, as well as controlled, efficient motions, are important components of microsurgical technique and success. An accurate and objective means of skill assessment is lacking in resident microsurgical education. Here we employ three-dimensional, real-time motion-tracking technology to analyze hand and instrument motion during microsurgical anastomoses.

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Objectives: The purpose of this study was to determine reference points for thermal perception in cutaneous lesions of leprosy, a disease caused by Mycobacterium leprae characterised by hypoesthesia in skin lesions due to nerve and Schwann cell infection. Early diagnosis is essential to control transmission and effectively treat the disease.

Methods: Quantitative thermal testing (QTT) has been proposed as a valuable tool for early detection of the disease, initiation of treatment, and monitoring of nerve damage.

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  • Understanding the interphase regions in epoxy resins is crucial for enhancing their mechanical properties, like fracture strength and barrier performance, as these areas are often weak spots.
  • Conventional methods struggle to analyze these nanoscale regions, making it hard to understand their formation processes.
  • By using molecular dynamics simulations and infrared mapping, researchers discovered that binding interactions of the amine cross-linker with various metal oxide surfaces affect binding energies, while also revealing that an excess of reactive materials remains near the particles, indicating potential undercuring in the matrix.
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  • - The study focused on cancer patients in Mbarara, Uganda, who developed infections after chemotherapy, aiming to assess the 30-day fatality rate and identify risk factors for mortality.
  • - Out of 150 patients studied, 42% died within 30 days, with pneumonia being the most common infection; factors such as high qSOFA and UVA scores were linked to increased mortality.
  • - The research concluded that the mortality rate for these infections was significant and highlighted the effectiveness of clinical risk scores (ECOG, qSOFA, UVA) in predicting patient outcomes.
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