Publications by authors named "S Losi"
Infantile occult exposure to cocaine in domestic environments represents a complex clinical and medico-legal problem, which can be associated with abuse and neglect and with potential short- and long-term health risks for children. The authors present a retrospective study on 764 children under 14 years old who accessed the Emergency Department of IRCCS Meyer from 2016 to 2023 and were included in the GAIA (Child and Adolescent Abuse Group) protocol for suspected maltreatment and abuse, and for which a urine toxicology analysis was performed. The aim is to discuss the medico-legal implications and highlight the need for a thorough evaluation and management of such situations.
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- Child abuse is often underestimated, leading to challenges for healthcare professionals and forensic pathologists in accurately diagnosing cases, especially when injuries mimic signs of abuse but have different causes.* -
- A study identified six instances (1.43%) of injuries initially thought to be abuse, which were later determined to be due to alternative medical practices or specific medical conditions following thorough examination by a multidisciplinary team.* -
- Awareness of "mimics" is vital for professionals to prevent diagnostic errors and ensure children receive the appropriate medical care, highlighting the need to differentiate between actual abuse and conditions caused by non-medical practices.*
Purpose: An Italian real-world retrospective study was conducted in patients with psoriasis (PSO) to evaluate their characteristics, treatment patterns, and biological/targeted synthetic disease-modifying antirheumatic drug (b/tsDMARD) drug utilization.
Patients And Methods: The retrospective analysis was carried out on real-world data collected from administrative databases of selected Italian health-departments; the dataset covered approximately 22% of the Italian population. PSO patients (identified by PSO hospitalization, and/or active exemption code and/or a topical anti-psoriatic medication prescription) were included.
Introduction: Moderate to severe atopic dermatitis (AD) is associated with a significant disease burden, impacting sleep, quality of life, and treatment needs. The aim of this study was to characterize disease burden and treatment patterns for adults with moderate to severe AD in three European countries: France, Italy, and the UK.
Methods: This retrospective analysis of adult patients with moderate to severe AD in Europe used medical records and physician/patient survey data collected in August 2019 to April 2020.
Article Synopsis
- The study analyzes the use of biological drugs in psoriatic arthritis (PsA) patients in Italy, focusing on treatment patterns and how often these drugs are prescribed from 2017 to 2020.
- A retrospective approach was used, analyzing data from hospitalization and exemption codes to identify patients, comparing those who had previously used biologics with those who had not.
- Results revealed that a significant percentage of PsA patients were untreated, while the use of TNF-inhibitors decreased in favor of IL-inhibitors, and around 55.6% of patients using ixekizumab were new to biological treatments.