Publications by authors named "S Lorente-Cebrian"
MicroRNAs play a pivotal role in the regulation of adipose tissue function and have emerged as promising therapeutic candidates for the management of obesity and associated comorbidities. Among them, miR-1 could be a potential biomarker for metabolic diseases and contribute to metabolic homeostasis. However, thorough research is required to fully elucidate the impact of miR-1 on human adipocyte thermogenesis and metabolism.
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- Eating foods high in polyphenols can help prevent long-term diseases, but we still need to learn more before making strong health recommendations!
- Future research needs to focus on how safe polyphenols are, how they work together, and how they interact with our gut bacteria for better diets!
- Scientists will also explore new ways to deliver polyphenols and understand how they can aid sports nutrition and recovery!
Background: Edible plants have been linked to the mitigation of metabolic disturbances in liver and adipose tissue, including the decrease of lipogenesis and the enhancement of lipolysis and adipocyte browning. In this context, plant microRNAs could be key bioactive molecules underlying the cross-kingdom beneficial effects of plants. This study sought to explore the impact of plant-derived microRNAs on the modulation of adipocyte and hepatocyte genes involved in metabolism and thermogenesis.
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- The Special Issue of the Journal of Physiology and Biochemistry highlights 7 contributions from the long-running "Consortium of Trans-Pyrenean Investigations on Obesity and Diabetes" (CTPIOD), which focuses on understanding obesity, diabetes, and related diseases.
- The research primarily involves collaborative efforts from groups in France and Spain, but invites participation from other countries as well, emphasizing molecular and physiological mechanisms, prevention, and therapy.
- Many contributions stem from the 19th Conference held in Jaca, Spain, where lectures discussed the role of specific fatty acids and phytochemicals in preventing metabolic disorders, prompting original research submissions for this issue.
MicroRNAs (miRNAs) are small single-stranded non-coding RNA molecules that regulate gene expression at the post-transcriptional level. A cross-kingdom regulatory function has been unveiled for plant miRNAs (xenomiRs), which could shape inter-species interactions of plants with other organisms (bacteria and humans) and thus, be key functional molecules of plant-based food in mammals. However, discrepancies regarding the stability and bioavailability of dietary plant miRNAs on the host cast in doubt whether these molecules could have a significant impact on human physiology.
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