Publications by authors named "S Lopez-Garcia"
Objective: To assess the efficacy and safety of subcutaneous perispinal infiltration of low dose of triamcinolone and lidocaine indicated for pain control in patients with cervical osteoarthritis (COA).
Methods: Patients with symptomatic COA resistant to conventional treatment including anti-inflammatory drugs, analgesics, and physical therapy were included. Technetium-99 m pyrophosphate (99mTc-PYP) scintigraphy and computerized tomography (CT) fusion scans images were used for diagnosis of COA and as a guide for level(s) of infiltration(s).
Background: The advent of Alzheimer's disease-modifying drugs requires accurate biological diagnosis to identify candidates for these therapies. So far, the most promising single plasma biomarker is phosphorylated tau at threonine 217 (p-tau217). To understand its biological features, it is essential to know its longitudinal trajectory and factors influencing it in cognitively unimpaired subjects with no brain pathology.
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- - The study focuses on the effectiveness of the fully-automated Lumipulse plasma p-tau217 assay as a diagnostic tool for early Alzheimer’s disease (AD) by measuring plasma biomarkers that indicate amyloid deposition in the brain.
- - Researchers analyzed blood samples from 209 cognitively healthy participants, finding significant correlations between plasma p-tau217 levels and established CSF biomarkers for AD, indicating its potential for early detection.
- - The results demonstrated that plasma p-tau217 levels were markedly higher in participants with positive amyloid status (A+), with a high predictive value for amyloid pathology, suggesting its utility in clinical settings for identifying preclinical AD.
Article Synopsis
- The study investigated the cytotoxic effects of a biocompatible 3D-printed resin used in occlusal devices, focusing on how different UV post-processing methods and rinsing solvents affect human gingival fibroblasts (HGFs).
- Sample discs were tested using various assays to assess cytocompatibility, and the samples were divided into groups based on the post-processing methods, including two types of UV polymerization and two rinsing solvents.
- Results showed no significant differences in cytotoxicity across the different post-processing methods, indicating that all methods were equally safe for human gingival fibroblasts compared to the control group.
The purpose of this study was to assess the external load demands in futsal, considering both home and away matches and their outcomes, in order to plan microcycles throughout the season based on the external load of each match. The external load of 10 players from a First Division team in the Spanish Futsal League was recorded throughout 15 official matches in the first half of the league championship. The players' external load was monitored using OLIVER devices.
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